Har yaushe za ku iya ɗaukar berberine?

2023-11-02 11:08:35

Berberine wani emulsion ne da aka kafa a cikin shaguna da yawa kama da goldenseal, barberry, da innabi na Oregon. Ya zo sanannen kari na ganye saboda fa'idodin fa'idodin kiwon lafiya da yawa. Har yanzu, tambayoyi sun kasance game da amincin shan berberine na dogon lokaci. Anan ne duba fa'idodi da rashin amfani na tsawaita amfani da mafi kyawun ayyuka don shan abubuwan berberine akan lokaci.

Fa'idodin Lafiyar Berberi

Berberine Hydrochloride foda an yi amfani da shi a cikin magungunan gargajiya na kasar Sin tsawon ƙarni don magance cututtuka daban-daban. Bincike na zamani ya tabbatar da wasu fa'idodin nazarin halittu masu amfani da berberine:

Taimakawa Lafiyar Zuciya

Berberine na iya taimakawa wajen tallafawa lafiyar zuciya ta hanyoyi da yawa:

- Yanayin Cholesterol - Nazarin ya nuna berberine zai iya taimakawa rage LDL (mummunan) cholesterol da triglycerides, yayin da yake haɓaka HDL (mai kyau) cholesterol. Wannan yana yiwuwa saboda iyawar berberine don rage ma'ajiyar kitse a cikin hanta.(1)(2)

- Barazana na zuciya - Ta hanyar daidaita matakan cholesterol da yanayin lipid na jini, berberine na iya rage abubuwan barazanar da ke hade da bugun jini, bugun zuciya, da gunaguni na zuciya.(3)

Sarrafa Matakan Sugar Jini

Bincike ya nuna cewa berberine na iya zama da amfani don kammala alamun glucose metabolism da fahimtar insulin:

- Fahimtar Insulin – Berberine yana kunna enzyme AMP-actuated protein kinase (AMPK) .Wannan yana haɓaka ikon sel don ɗaukar glucose, ta haka yana haɓaka haɓakar insulin.[4].

Glucose metabolism - Berberine yana bayyana a cikin metabolism da aikace-aikacen glucose. Hakanan yana iya tallafawa yanayin haemoglobin A1C mai lafiya a da a cikin kewayon al'ada.(5)

Inganta Lafiyar Narkar da Abinci

Berberine hydrochloride An yi amfani da shi a al'ada don magance matsalolin gastrointestinal. Bincike ya tabbatar da cewa yana iya:

- Lafiyar Gut - Berberine yana nuna ayyukan antimicrobial akan ƙwayoyin cuta daban-daban waɗanda ke cikin lamuran narkewar abinci. Yana kuma bayyana yana inganta mutuncin rufin hanji[6].

- Zawo - Berberine yana rage gudawa masu haifar da kwayoyin cuta da kuma fitar da ruwan hanji. Bincike ya nuna zai iya taimakawa wajen magance zawo mai saurin yaduwa.[7]

Hatsarin Yiwuwar Amfani da Berberine na Dogon Lokaci

Duk da yake berberine yana da tarihin amfani mai yawa na aminci, akwai wasu haɗari masu haɗari waɗanda ke da alaƙa da kari na dogon lokaci don la'akari.

Hankalin narkewar abinci

- Kayayyakin gefe- Lokacin da aka ɗauka a cikin manyan boluses, berberine na iya haifar da damuwa na narkewa, damuwa, tashin zuciya ko gudawa a wasu ɗaiɗaikun mutane. Wadannan kayan gefen sun bayyana sun dogara da magani.(8)

- Kulawa da likitanci - Tsawaita amfani da berberine na iya yin illa ga matsalolin narkewar abinci da suka kasance a baya. Wadanda ke da tarihin yanayin GI yakamata suyi amfani da berberine a ƙarƙashin kulawar likita.

Ma'amala da Magunguna

- Metabolism na miyagun ƙwayoyi - Berberine na iya hana CYP450 enzymes da ke cikin ƙwayar ƙwayar cuta. Wannan na iya haifar da tarin magunguna masu guba a cikin jiki idan aka sha na dogon lokaci.[9]

- Shawarar likita - Duk wanda ke shan magungunan magani ya kamata ya yi magana da likitansa kafin ya sha berberine na dogon lokaci saboda haɗarin hulɗar juna.

Tasiri kan Ayyukan Hanta

- Yawan allurai - Wasu nazarin dabbobi suna ba da rahoton gazawar aikin hanta da yuwuwar lalacewar hanta tare da babban adadin berberine.[10]

- Tsanaki na dogon lokaci - Yayin da berberine yana da tarihin amfani da yawa, akwai iyakataccen bayanan asibiti akan tasirinsa na dogon lokaci akan hanta. Ana ba da shawarar saka idanu lokaci-lokaci.

Mafi kyawun Ayyuka don ɗaukar Berberine Dogon Lokaci

Masu sha'awar haɗawa da berberine a cikin aikin zaman lafiya na dogon lokaci ya kamata su bi waɗannan mafi kyawun ayyuka don rage haɗarin haɗari:

Abubuwan da aka Shawarar

- ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun yanayi - Ana amfani da allurai na 900-1500 MG kowace rana don sarrafa matakan sukari na jini da cututtukan GI. Ƙananan allurai na 500-1000 MG kowace rana sun dace da lafiyar gaba ɗaya.[11]

- Kauce wa wuce gona da iri - Don hana illa, jimlar shan berberine kada ya wuce 2 g kowace rana. Zai fi kyau a zauna a ƙasa da 1 g kowace rana sai dai idan an kula da lafiyar ku.[12]

Saka idanu da Saka idanu 

- Gwajin bin diddigin - Yi aikin jini lokaci-lokaci don saka idanu enzymes hanta, lipids na jini, da sukari na jini. Kula da alamun hulɗa tare da magunguna.

- Daidaita kamar yadda ake buƙata - Ƙara ko rage sashi dangane da sakamakon lab, ma'aunin kiwon lafiya da aka sa ido, da jagora daga mai ba da lafiyar ku.

Amfani da Kekuna Berberine

- Kunnawa / kashe hawan keke - Yi la'akari da yin amfani da berberine ta hanyar ɗaukar shi na wasu watanni, sannan ku huta kafin fara wani zagaye. Wannan na iya taimakawa rage haɗari tare da tsawaita amfani.

- Tuntuɓi likitan ku - Samun shawarar likita don ƙayyade amintaccen kunnawa / kashe mitar sake zagayowar da tsawon lokaci dangane da matsayin lafiyar ku da burin ku don ƙarin berberine.

Me zai faru idan kun sha Berberine na dogon lokaci?

Shan babban allurai na berberine na dogon lokaci ba tare da kulawar likita ba na iya haifar da:

- Hankalin narkewa, tashin hankali, tashin zuciya, gudawa[13]

- Mu'amalar magunguna masu haɗari daga tarawa[14]

- Rashin aikin hanta ko haɓakar enzymes hanta[15]

- Rashin daidaituwar abinci mai gina jiki daga al'amuran malabsorption na dogon lokaci[16]

Ya kamata a sha Berberine a matakan da aka ba da shawarar. Duk wanda ke fuskantar illa ya kamata ya daina amfani da shi kuma ya ga likita don kawar da matsalolin da ke cikin tushe.

Shin ya kamata ku kashe Berberine?

Yin keken keke na berberine na wasu lokuta na iya zama da hankali don rage duk wata haɗari. Wasu shawarwari sun haɗa da:

- Sha berberine na tsawon makonni 12, sannan a yi hutu na mako 4[17].

- Madadin watanni 2-3 akan berberine tare da hutun wata 1[18]

Bincika tare da mai ba da kiwon lafiya don keɓaɓɓen shawarwari game da berberine kekuna da haɗa hutu don guje wa illa.

Shin akwai illa ga shan Berberine?

Abubuwan da za su iya haifar da ƙarin berberine na dogon lokaci na iya haɗawa da:

- Bacin rai, tashin zuciya, tashin zuciya a yawan allurai[19]

- Rage hawan jini, wanda zai iya zama cutarwa ga masu fama da hauhawar jini[20].

- Yin hulɗa tare da magunguna don ciwon sukari, kwantar da hankali, zubar jini, da sauransu[21].

- Iyakantaccen bayanan aminci ga mata masu ciki ko masu shayarwa[22]

- Rashin raunin bitamin K, maganin rigakafi na tetracycline [23]

- Mai yiwuwa gubar hanta bisa ga wasu nazarin dabbobi[24]

Kula da sigogi na kiwon lafiya da kasancewa a cikin shawarwarin da aka ba da shawarar na iya taimakawa rage haɗari lokacin shan berberine.

Yaya tsawon lokacin Berberine ke ɗauka don rage sukarin jini?

Bincike ya nuna berberine yana fara aiki da sauri don taimakawa tallafawa matakan sukarin jini masu lafiya waɗanda ke cikin kewayon al'ada:

- Yana rage sukarin jini cikin kwanaki 3[25]

- Yana rage yawan glucose na jini a cikin watanni 1-3[26]

- Yana inganta HbA1c a cikin watanni 2-3[27]

Tabbas, rage sukarin jini da yawa na iya zama haɗari. Ya kamata a kula da matakan glucose na jini lokacin fara berberine.

Yaya tsawon 500 MG Berberine ya zauna a cikin tsarin ku?

Akwai ƙayyadaddun karatu akan pharmacokinetics na berberine. Koyaya, ƙaramin bincike ɗaya a cikin mahalarta 6 ya sami:

- Matsakaicin matakin plasma ya kai kusan awanni 4 bayan kashi ɗaya na 500 MG[28]

- Har yanzu ana iya gano Berberine a cikin jini bayan awanni 24[29]

Fitsari ya ƙunshi metabolites na berberine kwanaki da yawa bayan kashi[30]

Don haka kashi ɗaya na 500 MG yana bayyana yana da tasirin da zai wuce kwana ɗaya. Koyaushe bi umarnin alamar.

Shin Berberine zai iya juyar da hanta mai kitse?

Wasu bincike na farko a cikin mutane da dabbobin dabba sun nuna cewa berberine na iya taimakawa wajen tallafawa aikin hanta lafiya:

- Yana rage yawan kitse da alamomin kumburi a cikin hanta[31].

- Yana inganta alamomin enzyme na aikin hanta[32]

- Antioxidant Properties na taimaka kare hanta Kwayoyin[33]

Ana buƙatar ƙarin karatun asibiti. Amma berberine yana nuna alƙawarin taimakawa wajen kula da kitsen hanta na yau da kullun a cikin kewayon lafiya.

Yaushe Ya Kamata Ka guji Berberine?

Berberine Hcl Foda ya kamata a guji a wasu yanayi saboda haɗarin haɗari:

-Mace masu ciki/masu shayarwa saboda rashin bayanan tsaro[34]

- Yin tiyata saboda hulɗa da maganin sa barci[35].  

- Kuna da ciwon hanta ko koda saboda haɗarin guba[36].

- A kan magunguna kamar masu rage jini waɗanda za su iya hulɗa da juna[37]

-Rashin G6PD, wanda ke ƙara haɗarin anemia na hemolytic[38]

Tabbas, duk wanda ke fuskantar illa daga berberine yakamata ya daina amfani. Nemi shawarar likita game da amfani da ya dace da kiyayewa don yanayin ku.

Kammalawa

Bincike ya nuna cewa berberine na iya ba da jijiyoyin jini, sarrafa sukarin jini, da fa'idodin narkewar abinci lokacin da aka ƙara ɗan gajeren lokaci a ƙarƙashin kulawar likita. Koyaya, akwai wasu yuwuwar haɗari kamar hanta mai guba don yin la'akari tare da tsawaita amfani. Aiwatar da ka'idojin hawan keke, zama cikin shawarwarin allurai, da sa ido kan sigogin lafiya na iya taimakawa rage haɗari. Duk wanda ke yin la'akari da ƙarin berberine na dogon lokaci ya kamata ya yi aiki tare da mai ba da lafiyar su don ƙayyade sigogi masu aminci waɗanda suka dace da matsayin lafiyar su da bukatun su.

Hubei Sanxin Biotechnology Co., Ltd. ya haɗu da bincike da haɓakawa, samarwa da tallace-tallace na shekaru masu yawa. Mu ne abin dogaronku Berberine Hydrochloride fodadillali. Za mu iya ba da sabis na musamman azaman buƙatarku.

email: nancy@sanxinbio.com

References

[1] https://pubmed.ncbi.nlm.nih.gov/29910305/

[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717611/

[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410031/

[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151392/

[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851353/

[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264771/

[7] https://pubmed.ncbi.nlm.nih.gov/17922955/

[8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814337/

[9] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717621/

[10] https://pubmed.ncbi.nlm.nih.gov/26092996/

[11] https://examine.com/supplements/berberine/

[12] https://www.nccih.nih.gov/health/berberine

[13] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814337/

[14] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717621/

[15] https://pubmed.ncbi.nlm.nih.gov/26092996/

[16] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717621/

[17] https://www.healthline.com/nutrition/berberine#TOC_TITLE_HDR_8

[18] https://blog.designsforhealth.com/sites/default/files/content/CommonSenseBerberine.pdf

[19] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814337/

[20] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717611/

[21] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773875/

[22] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870378/

[23] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717621/

[24] https://pubmed.ncbi.nlm.nih.gov/26092996/

[25] https://care.diabetesjournals.org/content/27/12/2995

[26] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410097/

[27] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851353/

[28] https://pubmed.ncbi.nlm.nih.gov/15640447/

[29] https://pubmed.ncbi.nlm.nih.gov/15640447/

[30] https://pubmed.ncbi.nlm.nih.gov/15640447/

[31] https://pubmed.ncbi.nlm.nih.gov/29910752/

[32] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449966/

[33] https://pubmed.ncbi.nlm.nih.gov/29910752/

[34] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870378/

[35] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717621/

[36] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717621/

[37] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773875/

[38] https://pubmed.ncbi.nlm.nih.gov/24771461/